Hyaluronidase,37326-33-3,IC-1118
Product Information
Biological Activity
Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been used as a local anesthetic additive[1][2].
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species
Mouse
Rat
Rabbit
Guinea pig
Hamster
Dog
Weight (kg)
0.02
0.15
1.8
0.4
0.08
10
Body Surface Area (m2)
0.007
0.025
0.15
0.05
0.02
0.5
Km factor
3
6
12
8
5
20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by (Animal B Km / Animal A Km)
Order Information
Quantity
Price($)
Price($)
Availability
10mg
$80.00
€88.00
In stock
100mg
$120.00
€132.00
In stock
500mg
$350.00
€385.00
In stock
Free Delivery on orders over $350.00.
Chemical Information
Molecular Weight
N/A
Formula
N/A
CAS Number
37326-33-3
Purity
>98.00%
Solubility
H2O :20 mg/mL
Storage
Store at -20¡ãC, protect from light
Reference
[1]Vartanian AJ, et al. Injected hyaluronidase reduces restylane-mediated cutaneous augmentation. Arch Facial Plast Surg. 2005 Jul-Aug;7(4):231-7.
[2] Brandon E, et al. The Use of Hyaluronidase in Cosmetic Dermatology: A Review of the Literature. J Clin Investigat Dermatol. 2015;3(2): 7.
We Devoted Ourselves To The Development Of Biomedical Research Reagent.
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
