MOTS-c(Polypeptide) |
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Cat.No.: |
IC-0918666 |
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Product Information |
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Biological Activity |
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MOTS-c is a mitochondrial-derived peptide. MOTS-c induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c induces glucose uptake and improves insulin sensitivity. MOTS-c has implications in the regulation of obesity, diabetes, exercise, and longevity[1]. |
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Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines) |
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Species |
Mouse |
Rat |
Rabbit |
Guinea pig |
Hamster |
Dog |
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Weight (kg) |
0.02 |
0.15 |
1.8 |
0.4 |
0.08 |
10 |
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Body Surface Area (m2) |
0.007 |
0.025 |
0.15 |
0.05 |
0.02 |
0.5 |
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Km factor |
3 |
6 |
12 |
8 |
5 |
20 |
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Animal A (mg/kg) = Animal B (mg/kg) multiplied by (Animal B Km / Animal A Km) |
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Order Information |
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Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
Quantity |
Price($) |
Price($) |
Availability |
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10mg |
$120.00 |
€132.00 |
In stock |
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50mg |
$350.00 |
€385.00 |
In stock |
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100mg |
$850.00 |
€935.00 |
In stock |
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Free Delivery on orders over $350.00. |
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Chemical Information |
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Molecular Weight |
2234.64 |
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Formula |
C103H156N28O24S2 |
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CAS Number |
N/A |
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Purity |
>98.50% |
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Solubility |
DMSO : 4 mg/mL (1.79 mM; Need ultrasonic) |
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Storage |
at -20¡ãC |
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Reference |
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[1]. Changhan Lee, et al. MOTS-c: A Novel Mitochondrial-Derived Peptide Regulating Muscle and Fat Metabolism. Free Radic Biol Med. 2016 Nov;100:182-187. |
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We Devoted Ourselves To The Development Of Biomedical Research Reagent. |
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